NVME M2 drives: which slot to use?

And also if the slot on the motherboard takes a B key, M key or a B+M key for the SSD?? If is not possible then

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m2 sata vs nvme slot 2 drives aren't connected to a motherboard via a cable, they're instead plugged directly into the motherboard using a dedicated connector

m2_1 slot expansion slot is the specification for internal expansion cards on computers' motherboards Intel first introduced slot in 2012 as